Thank you for your contributions to the BANC dataset! Proofreading is moving along at an impressive pace, with over half of the cells in the brain completed.
Today we ask for your help this holiday season by identifying specific visual projection cells in the right optic lobe: LC cells, LPCs, LLPCs and LPLCs. These cells enable the brain to recognize objects and sense movement, translating sight into behavior and decision making (think: should I run from this frog or fly toward that tasty banana). They are of great scientific interest in the BANC as we can finally see their connectivity to VNC. But they have not yet been identified in BANC. There are over 40 different types of LC cells.
Krzysztof has a great overview of these cells in this post.
Resources:
Find example cell types on the OL Boundary Cell Types page in Codex. Ctrl+F for LC, LPC, LLPC, LPLC
Thank you for your help in finding and identifying these cells in the BANC! If you have any questions, please feel free to add them in this thread. These cells will be added to the BANC-bot shortly and this post will be updated when they are.
Amy, Marissa, Mala, Sebastian, and the FlyWire team at Princeton
Cool! I’ll start right away.
It would be useful to have annotations defined for them though (including the hierarchy, like we have for the optic lobes’ ones).
For now, we can (probably) label them only as a freeform annotation.
Hooray! Good point about annotation list. We can work on tjos. If you would rather take the first pass, feel free! Marissa is double checking the correct OL
I’ve been working on collecting the LC4s into a single set. Up to 27 so far (FAFB had 50).
Do we have a clear way on identifying these yet? There are actually a few LC4s in the dataset (Neuroglancer) but I cannot figure out how that was added, unless it was before the current banc bot setup.
Edit: I’ve got 54 (two damaged/incomplete) LC4s now - there seems to be one or two missing based on the gap in the canopy but I haven’t been able to locate them. Set complete here: Neuroglancer
LC4s appear to be done (other than one or two I think are missing), outside of getting cell info added. Link’s above.
Since I’ve found a good bundle area to work from I’ll be continuing on LC types- next up is what appears to be LC12s as they are also common in the area I’m working from (might actually be two groups of LCs here). Neuroglancer
