What type of cell it is?

The reason given for requesting the full name as well as abbreviation when IDing a cell is that it is more easily searchable in the database. When searching “Medulla intrinsic” you’ll get very specific results, where as searching for “Mi” may make it more difficult to just gather information on just those cell types, as any word containing “mi…” will appear. Just thought I’d give a little more context for the naming conventions. Probably should also unbury it from this forum thread eventually as well but that’s for a time that’s not Friday evening :slight_smile:

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A little new to naming some of these. Is this an Lcn type? Link: FlyWire

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Good question! Answer from Sven (should I do a little post introducing everyone who is working on FlyWire?):

There are legitimate cases where the soma cannot be attached because it is:

a) outside of the volume (e.g. ascending, many sensory neuron)
b) outside of the segmented volume (in this case one can see it in the EM)

in those cases it is correct to mark it as complete without a soma.

I know it is unsatisfying to do all the work and not finish the cell, but it would be best to not do anything with it at that point. We will get to it eventually and all proofreading done on such cells will help the next person that tries to finish it (e.g. coming from the branch that could not be found by the Flyer)

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@Krzysztof_Kruk Nice, I found another one too (green cell)…definitely a type of group. They follow the same basic pattern as TmY’s (except for that lone neurite that terminates…elsewhere, lol). I’m gonna go stare at the Fischbach diagrams for a while…

https://ngl.flywire.ai/?json_url=https://globalv1.flywire-daf.com/nglstate/6610568836284416

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@AzureJay I am not at all familiar with Lobula Intrinsic neurons yet, but I’ll give you my take so far…

The Fischbach paper seems to suggest that Lcn neurons axon somewhere in the central brain (reference sections 3.4 and 3.4.1 of the Fischbach paper). The neuron you have shown doesn’t seem to arborize outside of the optic lobe, but rather arborizes exclusively in the Lobula, which fits the Fischbach description of a Lobula Intrinsic (Li) neuron (reference section 3.3.10 of the Fischbach paper). So, my best guess, at the moment, would be Li1 (Fig. 6 in the Fischbach paper).

Cheers.

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Oh, you’re right about the direction - I keep mentally flipping which side of the diagrams are “eye” side and which are central brain side.

I’m not confident with Li1, but looking at the structure perhaps Mt8?

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@AzureJay Attached is the diagram from Fischbach, showing Mt8. I have labeled the different neuropils (red), according to my interpretation of the diagram. If my interpretation is correct, then it looks like Mt8 arborizes in the medulla, and then sends off axons into the lobula and central brain…which doesn’t look like it matches the cell you posted (to me), although the border between the medulla and lobula can be a bit fuzzy, in our 3d mesh, lol. Let me go take a closer look…

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@AzureJay Yeah, here is a link to your cell, shown with the colored neuropils (easier to distinguish, lol). It looks like your cell arborizes exclusively in the lobula.

Let me know what you come up with, I’m interested to become more familiar with these “deep” neurons… :slight_smile:

https://ngl.flywire.ai/?json_url=https://globalv1.flywire-daf.com/nglstate/5250919629324288

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Okay, makes a lot more sense!

My concern with Li1 is that there is a second arbor here not shown in Fischbach (the reason I was eyeing Mt8 was that extra arbor, but it makes sense it’s not that). Li2 however is definitely not the case either. This may be either a differing type of Li1, or an Li yet identified. I’m going to mark it with notes as such in the cell ID system but if anyone else has further ideas please let us know (we love you researchers!).

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According to this image from AJ’s latest post in visuals thread, I was wrong, this isn’t a new thing, it’s either Y11 or Tlp13 if im not mistaken?

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Sounds good, thanks for the info and reply!

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@Nseraf Nice! Thank you for pointing that out…I definitely recognize Y11! :smiley:

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Great connecting the dots! I think it does look pretty close to Y11, other than the placement of the soma (which may or may not matter). Otherwise I would say that it is more likely some variant of TmY but I can’t quite place it either.

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i would say this is a Y11, i do not think either Y or Tip cells goes trough the medulla

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Found this interesting little thing, FlyWire, a tm or y type thingy?

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Tms have CBs around lamina. This one has it outside LOP. I guess, it’s a Y, but don’t know, which one. None of the six in Fischbach look similar to this one, to me. Maybe one of the newer ones (Y7 - Y12).

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Agreed with KK here. Most likely Y type, unable to find any examples to match. Would mark as “resembles Y type”.

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@annkri Agreed, 100%…that is the cell I was thinking of, when I saw @Nseraf 's post about Y11.

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Marked them all as Y11 (finished the one, that wasn’t already finished).

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@Krzysztof_Kruk Wait, which ones…these?

https://ngl.flywire.ai/?json_url=https://globalv1.flywire-daf.com/nglstate/6610568836284416

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